Prolactin Controls Mammary Gland Development via Direct and Indirect Mechanisms
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چکیده
منابع مشابه
Prolactin affects leptin action in the bovine mammary gland via the mammary fat pad.
One of the roles of the endocrine system is to synchronize mammary function. Hormones, such as estrogen, progesterone, and prolactin act directly on the mammary gland. Metabolic hormones, such as GH, glucocorticoids, insulin, and leptin are responsible for coordinating the body's response to metabolic homeostasis. Leptin has been shown to be an important factor in regulating the metabolic adapt...
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.................................................................................................................................................... 5 RÉSUMÉ .......................................................................................................................................................... 7 ACKNOWLEDGMENTS .....................................................................
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The mammary gland is a complex organ that begins development early in gestation and constantly changes in size, shape and function from the time of puberty to menopause. The earliest stages of embryogenesis appear to be independent of steroid hormones, whereas after the 15th week breast structure is largely influenced by a variety of hormones. In most females, further breast development begins ...
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Receptors for human, simian, ovine, bovine and murine prolactin, human growth hormone and human placental lactogen have been identified in plasma-membrane-containing subcellular particles isolated from rabbit mammary glands. The association and dissociation of (125)I-labelled prolactin are time- and temperature-dependent processes, both being maximal at 37 degrees C. (125)I-labelled prolactin p...
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a number of biological processes in vertebrates, including reproduction, growth and development, osmoregulation, metabolism and immunoregulation (Nicoll, 1974). The biological actions of prolactin have been most extensively characterized in the mammary gland, where it has an essential role both in the differentiation of the gland during pregnancy and in the regulation of milk protein gene expre...
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ژورنال
عنوان ژورنال: Developmental Biology
سال: 1999
ISSN: 0012-1606
DOI: 10.1006/dbio.1999.9271